| 21.09.2015 | 15:00 | Portland Timbers | vs | New York Red Bulls | Eurosport HD , Eurosport International / HD , Eurosport Nordic , ESPN Caribbean , Abu Dhabi Sports 4 HD |
| 21.09.2015 | 15:00 | River Plate | vs | Lanus | Sport TV2 (portugal) , Canal+Futbol , Digi Sport 1 (hun) , Arena Sport 3 (serbia) , Digi Sport 3 (romania) , Arena Sport 1 / HD (cro) , beIN Sport Max 9 , TV Publica , Sport TV Africa 2 / HD |
| 21.09.2015 | 15:00 | Coritiba | vs | Atletico Paranaense | PFC International |
| 21.09.2015 | 15:00 | Philadelphia Union | vs | Houston Dynamo | Eurosport HD , Eurosport International / HD , Eurosport Nordic , Abu Dhabi Sports 4 HD |
| 21.09.2015 | 15:00 | San Lorenzo | vs | Racing Club | Sport TV1 (portugal) , Canal + Futbol , Digi Sport 1 (hun) , Arena Sport 1 (serbia) , Sport TV Africa HD , Arena Sport 1 / HD (cro) , TV Publica |
| 21.09.2015 | 15:30 | Gençlerbirliği U21 | vs | Beşiktaş U21 | BJK TV |
| 21.09.2015 | 16:30 | Ural | vs | Krasnodar | NTV Plus Nash Futbol |
| 21.09.2015 | 19:00 | Dinamo Moscow | vs | Rubin Kazan | NTV Plus Nash Futbol |
| 21.09.2015 | 19:00 | Korona Kielce | vs | Gornik Leczna | Eurosport 2 HD , Eurosport 2 Nordic , EuroSport 2 (north east) / HD |
| 21.09.2015 | 20:00 | Esbjerg | vs | Randers FC | TV3 Sport 1 (den) / HD |
| 21.09.2015 | 20:00 | Gençlerbirliği | vs | Beşiktaş | LİG TV / HD |
| 21.09.2015 | 20:00 | Hodd | vs | Sogndal | TV2 Zebra |
| 21.09.2015 | 20:00 | Ranheim | vs | Brann | C More Fotball (nor) / HD |
| 21.09.2015 | 20:05 | Örebro | vs | Elfsborg | C More Live 3 (nor/swe) , C More Sport (swe) , C More Sport (fin/swe) HD |
| 21.09.2015 | 20:30 | Utsiktens BK | vs | GAIS | TV4 Sport (sweden) |
| 21.09.2015 | 20:55 | Hapoel Beer Sheva | vs | Maccabi Haifa | IBA Channel 1 , The Israeli Network |
| 21.09.2015 | 21:00 | Manchester United U21 | vs | Everton U21 | MUTV |
| 21.09.2015 | 21:00 | Skenderbeu Korçe | vs | KF Tirana | SuperSport 3 HD (alb) |
| 21.09.2015 | 21:00 | Sporting Braga | vs | Maritimo | Sport TV1 (portugal) , Sport TV Africa HD , SportKlub 3 (croatia) , SportKlub 3 (serbia) , SportKlub 3 (slovenia) , Tivibu Spor / HD |
| 21.09.2015 | 21:00 | Steaua Bucarest | vs | Concordia Chiajna | Digi Sport 1 (romania) , Dolce Sport / HD , Look TV (romania) / HD |
| 21.09.2015 | 21:15 | Hessen Kassel | vs | Waldhof Mannheim 07 | Sport 1 (germany) / HD |
| 21.09.2015 | 21:30 | Ternana | vs | Livorno | Sky Sport 1 (Italia) , Sky Calcio 1 / HD , SuperSport 4 HD (alb) , Abu Dhabi Sports 5 HD |
| 21.09.2015 | 21:30 | Valenciennes | vs | Lens | Eurosport 2 France |
| 21.09.2015 | 21:45 | Derby County | vs | Burnley | Sky Sports 1 (uk) , SuperSport 5 [ZA] , SportDigital.tv , beIN Sports FR 1 / HD , TV2 Sport Premium HD , SportKlub 2 (slovenia) , SportKlub 2 (cro/srb) / HD |
| 21.09.2015 | 21:45 | Reading U21 | vs | Southampton U21 | SuperSport 3 [Za] , BT Sport 1 / HD , Fox Sports (italy) / HD |
| 21.09.2015 | 23:00 | Sporting Lisbon | vs | Nacional | Sport TV1 (portugal) , RTP International , SportKlub (Srb) / HD , SportKlub (Slovenia) , SportKlub (Croatia) , Telekanal Futbol , Sport TV Africa HD , Tivibu Spor / HD , BT Sport Europe / HD |